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All of the research in the last decade has shown that there are many, many more factors in weight loss than a linear caloric calculation. Genes getting turned on and off by certain substances is fascinating, for example. And the work being done at Harvard on hunger cycles is equally interesting: if you allow your body to get hungry each day (16-18 hours without intake of anything that trips the glycemic response), you can literally eat more calories per day than if you don't. The body is complex and still not understood in many ways and the traditional nutritionist profession has been making a mess of things with their certainty, which changes every 5 years.