I've seen this idea of playing Hoyer thrown around and it sort of boggles my mind that people genuinely feel that way.
Because the offensive line might not play well due to personnel changes, we should not start our best quarterback? The quarterback who gives the team the best chance to succeed should not play because something bad might happen? On a 1-3 team that needs a win?
I'm not one who's big on "loser mentality" tropes and I understand that sometimes it's smart to be pragmatic, but the idea of playing Hoyer is pretty darn weak, IMO. Do you think Tom Brady would have that mentality - if his starting offensive line was out, that he'd rather not play because the offense might struggle and he might get hurt? Weaksauce.
Show some mental toughness and go out there and execute at a high level with the players who are available.