They do feel a little different, but I've played pickup football games in the snow and cold plenty of times, and never really had a problem handling the football. You adjust very quickly. The bigger issues are slipping or sliding in the snow, or finding that acceleration and cuts are a bit harder to make. I don't think the field will be covered in snow, however, so that shouldn't be an issue.
We played the Bills close each time, and split with them in case some of the doom and gloom crowd forgets, so I'm not too concerned about this game. If JC holds onto that interception in the last game, we probably pull off the comeback. I expect the defense to come out with a bit of a chip on their shoulders after the way they let the Bills score on them. This will probably be a 27-24 kind of game, but I'd like to think we can pull off the win. The cold weather may impact some play calls, but otherwise it will be a slugfest, and should be exciting!