I originally thought this would be the day Maye would start but I have already resigned myself to the fact that it's not happening. With how many injuries they are now dealing with on the OL, I get it. Rough situation for a rookie learning the game.
Even with Jacoby it is a winnable game. Hopefully they can scoot through with the ground game and then get some better OL health for the next week. The Houston game will be a loss in all likelihood regardless. The Jacksonville game is, hopefully, winnable in London with a healthier OL and some other guys possibly back. If that's all correct, you're looking at being 3-4, while being 3-2 in the conference and 1-1 in the division.
Then it's back for a home game against the Jets. I think this might be a new sensible target game for Drake if the OL is healthier. It's an opponent he has seen on film already and it's at home. After that, the next 6 games are not too rough - at Tennessee, at Chicago, home vs LA Rams, at Miami, home vs Indianapolis, BYE, at Arizona - before finishing the final 3 tougher games at Buffalo, home vs LA Chargers, and home vs Buffalo.