If I'm Bill O'Brien, I don't want Clowney up against Cannon. I line him up against Solder and Thuney. I probably also like Wilfork up shaded to Andrews left, again putting pressure on Thuney.. Then I have McKinney come in late through the Right side A-gap.. Mercilus will be the Wild Card.. If you have him lined up next to Clowney, you're over-loading that side.. If you put Mercilus on the to Brady's right, he'll typically line up against a TE and may have the advantage over the likes of Bennett or Lengle.
Whatever happens, it's going to be a tough game..