1st rounders are the lifeblood of any team.
Without them, you're going nowhere.
If you're going to trade them, there are only 2 reasons for doing so. One, to grab a 24 year old player like AJ Brown (what the Eagles did) or because you are so stocked up at all positions that you can afford to let go of your future to insure a Super Bowl run.
I find it really odd and telling that the Patriots/Belichick were heavily criticized for horrible drafting during the 2014-2019 era when they traded away multiple picks, lost picks due to scandal, blew picks, and yet, during the entire period, they were in the Super Bowl or else in contention (2015).
So, they sold the future to win now, and they won.
But the talent depletion was real.