Contrary to apparent popular belief, this could have some wheels to it.
First off, I am a Patriots fan and Miami Hurricanes fans, so I know this guy like the back of my hand.
Andre Johnson is a leader; a quiet man who keeps to himself and leads by example. Despite many tough years: coaching changes, lack of of solid QBs, lack of secondary targets, etc., Johnson always remained calm and collected and never gave the media much to talk about.
However, last season you could see him visibly frustrated by the offensive play, specifically QB/coaching and overall regression from the successful year prior.
I truly believe that #80 WOULD indeed restructure his contract if a similar scenario arose. His body language last year was an illustration of a frustrated player without an answer.
With his salary, I doubt they'd be able to net much around the league, which to me, at least makes it a POSSIBLE outcome.