This game as do most games, come down to the 2 lines.
1. Can the DL create pressure on goff like they did against Rivers/Mahomes? Of the three quarterbacks, Goff is the lesser. If they can generate the amount of pressure against him that they did against them there is a good chance he gets flustered or throws a few our way.
2. Can our offensive line/run game dominate as they did against the chargers/KC? Patriots basically said we are tougher than you and ran it down their throats. By the end of those games the opposing defense didnt even want to tackle them. If they can do that to the Rams, I dont think Goff has the ability to do what mahomes did. which is stand in the pressure and make ridiculous throws.