Trying to defend Lewis and Gronk seems almost like a lost cause so I would put my energy into shutting down Edelman. Double Edelman at all times and mix up some coverages. As a defense I would try to force the ball Amendola's direction. Defensive line should focus on batting passes and ignore play action.
I would purposely let Blount have moderate success so that they dont abandon the run. I would constantly gamble on first down with blitzes that would force Brady to his left. Fleming is the weak link.