Honestly, I'm not sure there's any position other than QB I'd be upset drafting with our top pick. I just want us to draft someone who's awesome. The only players on our roster that I actually expect to actually give a damn about whether they're onthe roster or not in 3 years are:
QB Drake Maye
CB Christian Gonzalez
DT Christian Barmore
EDGE Keoin White
Guys like Douglas, Onwenu, Stevenson, Dugger, Peppers (if he's back), Marcus Jones, Boutte, Mapu, some of the younger OL are ok to have but don't seem anything special to me. I wouldn't be out on drafting someone who pushes them off the roster or reduces their role if the new guy is an actually elite player. Guys like Henry, Bourne, Wise, Andrews, Bentley, Tavai, Jon Jones are all likely off the team in 3 years or shells of themselves.
I just don't think one of the worst teams in the NFL without very many "core pieces" should be pigeon holing themselves into one specific positions or even a few of them. You can talk positional needs but even some of the best teams in the NFL have positional weaknesses. Everyone does. People obsess over the OL and I agree it's the biggest area of need because of what it can do for the rest of the offense, but it's not like we haven't seen teams make the super bowl before while still feeling they need help on the OL (Chiefs in 2020, Bengals a few years ago, etc.). What's really holding us back from being a contender isn't any one position group it's the fact that we don't have ANY truly elite players. Even of the core pieces I listed above, Maye is a developing rookie and Gonzalez/White show promise but aren't elite players right now. Maybe you could argue Barmore was elite last year (or could argue he was a tier below) and he's recovering from a serious health scare anyway.
It'd be a beautiful, beautiful thing if they draft a LT and he ends up a 8 time pro bowler. But what if they draft a LT and he's a good, not great player like Nate Solder was when we drafted him mid 1st? That's not some crazy low projection even for a LT we draf at #5, #6 or whatever pick we land at. It'd for sure be a nice and valuable improvement to lock that position down with competence and solid starter level play, but in the grand scheme of things that wouldn't do as much for us as a Will Anderson caliber edge player if you think someone on the board at another spot has that kind of potential. Even though guard is way less important than LT I'd take a Quentin Nelson type over a Nate Solder type. I'd take a Richard Seymour caliber DL. And on and on with whatever position you want to fill in with.
To ever be a contender again we're going to need to plug multiple positional weaknesses and add elite players across the roster. Elite players are harder to land so that has to be the priority, regardless of positions IMO.