In a game where you are lucky to posses the ball 12 times, throwing 2 picks,fumbling and allowing a safety is giving up 1/3of your offensive possessions.
Considering that Peyton could only lead his team to 8 points, allowing 9 directly off a safety and a pick 6 plus XP means Manning's mistakes directly cost his team more points than they scored. Thats not factorimg in even the other points scored after his other turnovers.
Seattle didn.t need any other offense other than that offered directly to them by Peyton
So 43-8 or 9-8, either way Denver loses because he could not overcome the deficit directly created by himself..