The 49ers have been decimated with injuries this year.
From last week:
Questionable
T Anthony Davis (shoulder), TE Vernon Davis (hamstring), S Raymond Ventrone (concussion), WR Kyle Williams (rib, knee), LB Patrick Willis (groin)
Probable
LB Navorro Bowman (wrist), C Jonathan Goodwin (elbow), RB Frank Gore (knee), G Mike Iupati (shoulder), DT Ray McDonald (ankle, ankle), CB Carlos Rogers (knee), DT Justin Smith (shoulder)
From last week's game LT Joe Staley got his leg bent backward at the knee and WR Quinton Patton has a fractured foot. WR Mario Manningham and WR Michael Crabtree are both on Reserve/PUP, they have six players on Reserve/NFI (DT Tank Carradine, DL Quinton Dial, RB Marcus Lattimore, OT Luke Marquardt, LB Aldon Smith and CB Eric Wright), and LB Nick Moody is on in-season IR. Last week LB Patrick Willis and CB Nnamdi Asomugha were both inactive with injuries, while RB LaMichael James has only been active for one game and TE Vernon Davis hasn't been much of a factor since week one due to his hamstring.
With all their injuries it's no wonder the 49ers have not looked sharp this season. All teams have to deal with ailments but somewhere there is a tipping point. Last week they got away with a win despite playing without two of their three All-Pro linebackers; that might work against the Rams, but it won't fly against most NFL teams.
I'll be curious to see how Cunningham performs against the Texans. San Francisco only signed him to a one-year deal, which makes me think that this is only temporary and he is not in their long-range plans.
