I would seriously consider sitting Gronk because he gets targeted so much. Brady not so much, he is more critical but QBs are also more protected and he can do things better/easier to protect himself (dumping the ball) than Gronk can.
Revis; although also another critical player; but he is not so likely to get hurt back there. VW is a guy who I think is more one who should be rested a little, especially as he plays in traffic.
In general I dont like the strategy of pulling certain guys and saying you are more important than the others (even if it is true). I think there is a 2d order [bad] effect to doing this. .... If you start pulling guys; you are telling the rest of the team 'this game is not important, dont play all out'. I think there is evidence that when guys play half-hearted in a game like this; the incidence of injuries increases 3x. Plus it just sets the team up to ingrain some bad habits for the next game, which is a 'come home with your shields or on them' scenario.
So, I would probably play everybody and then just let Grap play the 2d half to gain experience - not to protect TB, and then call player packages in 2d half that somehow dont require Gronk or VW to be out there. Not officially "pull them from the game"; but rather play them really sparingly in Qtrs 3-4.