The NFL no longer wants teams to play on the first Thursday night if that game could go on to decide homefield later in the season. The Colts arranged this after the last time they opened vs each other.
Colts vs Saints makes the most sense.
Pats will likely open on the road since there is a Buffet concert in the Razor that weekend. I see Pats at Ravens in week 1, possibly as a MNF or Sunday Night game. Remember, too, the US Open tennis final is on Sunday at 4:00 meaning CBS will not have a 4:00 game, so most AFC west coast teams are on the road in week 1.
Pats at Colts sometime in late October/early November.
Pats at Boys on Thanksgiving.
Pats vs Jets on MNF on X-mas eve.