Regarding non-contact injuries, interesting article on some reasons on why they may occur and some thoughts on prevention..
Why Minimal or Non-Contact Injuries Occur in NFL Workouts
This stood out:
"Interestingly, in 2010, Dr. Barry P. Boden and colleagues published a
study in the
Journal of the American Academy of Orthopedic Surgery that may relate to Lee's injury. In the study, the authors suggest landing on either a flat foot or the back of the foot may predispose to ACL injury—as may a flexed hip at the time of impact—along with several other factors. Indeed, Lee landed on his heel with his thigh bent upward."
Non-contact ACL Injuries: Mechanisms and Risk Factors
Most of that study's a bit beyond me, but it does suggest that while there's no avoiding plenty of injuries, there may be strategies or approaches that could mitigate others.