This game doesn't seem that hard to figure to me. Maybe I oversimplify, but I don't see a blow out.
The Giants are going to be able to move the ball and get points. Hopefully, we'll limit them to field goals, but I don't think we'll be as good at that as we were against the Chargers. I believe those who say something has "clicked" with Manning, and I don't expect a return of the old Eli. I hope for it, but I certainly don't expect it. They are going to get Plaxico isolated on Hobbs, and they are going to have a decent run/pass mix. They are going to score points.
I think the significant question in this game will be how their defense plays against our offense. No matter how one looks at it, there is going to be an advantage available for our offense somewhere on the field on pretty much every play.
The game, then, comes down to two very simple questions: (1) To win this game, the Giants will need to disguise their defenses. Can our coaching staff and QB figure out what they are doing in this regard and address it on the fly? (2) Is Tom Brady going to have enough time to find the mismatch?
I don't know the answer to those questions, and I think they will decide the game. What I do know is that there is no coach or staff I would rather have in the NFL trying to work on number 1. And there is no QB -- perhaps in the history of the game (at least as long as I've been watching) -- that I would rather have working on issue number 2. The offensive line has to hold up its end of the deal.