Picks:

The Patriots-Bills game highlights the early Sunday afternoon action, and then Dallas at Philadelphia follows as the big late game. The two prime time games are both well worth watching: Seattle travels to Green Bay in a rematch of January’s NFC championship game on Sunday night, and then on Monday night the Colts will attempt to fix their offensive line issues against a Jets team that recorded three sacks and forced five turnovers last week …

NFL Week Two kicks off Thursday night on CBS with a compelling matchup as the Denver Broncos travel to Arrowhead Stadium to take on the Kansas City Chiefs. These two division rivals both won last week, though the Chiefs did it in convincing fashion on the road at Houston, while Denver escaped with a home victory against Baltimore…

The first Sunday of the 2015 NFL season brings us some intriguing matchups. The best early game will be in Buffalo where Rex Ryan makes his coaching debut for the Bills, against this off-season’s most hyped player (Andrew Luck) and team (Indianapolis); the Colts are 2½ point road favorites in a classic battle between a good offense/bad defense and a good defense/bad offense. In the late afternoon two of the top AFC teams meet as Baltimore travels to Denver…

While all the hype this week is on Jim Harbaugh’s home debut as head coach of the Michigan Wolverines, the best game on Saturday is across the state in East Lansing where #5 Michigan State hosts #7 Oregon.