If you are speaking as a guitarist and consider Prince a "virtuoso," your horizons need expanding. As far as I know, he never released a guitar album, only played guitar in the context of his songs. He WAS talented, he was a GOOD guitar player, not a virtuoso. Compare his playing to that of the players below. He does not approach most in their overall command of tone/phrasing/lyricality/timing.
Guitar virtuosos, off the top of my head. (If you are unfamiliar with them, look them up; most are in the realm of popular/rock music. I intentionally am excluding contemporary fusion/jazz/neoclassical guitar virtuosos.) If I sat down and thought about it I'd come up with more:
Uli Jon Roth
Steve Hackett
Michael Schenker
Carlos Santana
Leslie West
Ritchie Blackmore
Joe Satriani
Steve Vai
Steve Morse
Paul Gilbert
Todd Grubbs
Travis Larson
John Petrucci
Chris Poland
Marty Friedman
Eric Johnson
Martin Barre
Dweezil Zappa
Yngwie Malmsteen
Zakk Wylde
Eddie Van Halen
Tony Iommi
Jason Becker
Ted Nugent
Robert Fripp
Adrian Belew
Alex Lifeson
Vivian Campbell
Alex Skolnick
David Gilmour
Jeff Beck
Try topping that list off the top of your head ... I double-dare you!
Let me know when you want to talk keyboardists.