Pittsburgh (-8) is the only team favored by more than a touchdown this week. Tennessee (at Miami), Kansas City (at Houston) and Minnesota (at Chicago) join New England at Tampa as the Week 5 road favorites.

Week five kicks off with a highly unusual occurrence: a great Thursday night matchup. The New England Patriots travel to Tampa Bay for Tom Brady’s first-ever regular season game on Dale Mabry Highway. The last time the Pats played in Tampa their quarterback was Trent Dilfer. Still donning creamsicle uniforms and a winking pirate, that was the Bucs first winning season in sixteen years.