I've given up on predictions, so I let Madden 13 do it for me.
Patriots 27, Dolphins 24
Patriots lead 24-0 just before halftime but barely win. Brady's touchdown streak ends and he goes a pedestrian 15-22 175 yds 1 INT. Ridley runs it 32(!) times for just 90 yards, but scores all three Patriots touchdowns. Tannehill throws for 365 yards and 3 touchdowns but is also picked off four times. Reggie Bush: 10 carries, 0 yards.
I could see most of this happening. I wouldn't be surprised if the Patriots stuck to the run no matter how ineffective it is. Weirder things have happened.