The Patriots appear to have suffered a big blow, with linebacker Jerod Mayo going down in the second quarter of Sunday’s game with an apparent knee injury. (FILE:Icon/SMI)

After losing defensive lineman Kyle Love in the first quarter, the Patriots suffered another tough blow on the defensive side of the ball in the second.

Linebacker Jerod Mayo went down during a play where he was seen wrestling with Raiders offensive lineman Steve Wisniewski, and appeared to plant awkwardly with his left knee.

After the play was over, the veteran linebacker hobbled a bit before going down, with Mike Giardi of CSNNE saying via Twitter that Mayo was seen slamming his helmet down on the sideline as he was attended to by trainers.

The team inserted Gary Guyton to replace him. ¬†He’s officially listed as questionable to return, but the early indications certainly don’t look promising.

According to Ian Rapoport, he reported via Twitter that Mayo took a cart back to the locker room and didn’t look to be bending his leg, although he did appear to put some weight on it.

Needless to say, it’s something we’ll have to continue to keep an eye on.