I know it's a completely different scenario, but I'm thinking of Kevin Durant and how I felt he should not have tried coming back against the Raptors. He sustained a much greater injury as a result and, even though he got the mega deal anyway, probably has altered the twilight of his career to some degree. Of course I'm not a doctor so I have no way of really knowing for sure, but certain injuries, like the ones being discussed, have lingering effects more often than not.
Again, I wish the best to Mahomes. He's a great young player and good for a league that does enough to hurt its own product.