Anything can happen. But this team has more top end talent AND more depth than ever before, even at the QB position. Last year, we knew Brady was suspended, but none of us had any clue, really, what JG could do. Now (assuming JG is still on the team at the start of the year) I think all of us would conclude that even if Brady missed large chunks of time, the team is in good hands at QB.
That said, I fully expect them to win 12+ games and be in the AFCCG. They are, on paper, the best team in the AFC (the best team in football actually), but getting to the Super Bowl might come down to where the AFCCG is played. They seem to have a very difficult schedule this year and so 12-4 might be a good mark, but there might be another team that goes 13-3. If the Pats have to go on the road for the AFCCG, they could lose. And, of course, winning the Super Bowl, even when the Patriots have had great teams, has NEVER been easy.
So 12+ wins and making it to the AFCCG. I'll take my chances from there.