Not this year. If you actually take Nick's 575 receiving yards from Eli Manning's passing total of 2377 yards, he still has passed for more yards than Sanchez 1802 to 1775 (which basically disproves your theory that the Jets receivers are significantly better than the Giants' receivers without Nicks). And everyone knows it doesn't work that way because if the Giants didn't have Nick all season, someone would have gotten at least part of that 575 yards Nick has so far this season.
Victor Cruz has more yards than Santonio Holmes (588 to 340). Both have four TDs. Cruz also crushed Holmes in yards per catch 17.3 to 13.6.
Plaxico Burress has an edge over Mario Manningham by on yard, three TDs, and 2 yards per catch, but Burress is a #2 WR and Manningham has been the #3 WR until this past weekend with two WRs ahead of him destined barring injuries to get over 1,000 a piece.
Dustin Keller has a minor lead in yards over Jake Ballard 436 to 395. But Ballard has more TDs and a better yards per catch (17.3 vs. 15.0)
LT is a better receiver than Brandon Jacobs. Kerley is better than the third WR for the Giants this past weekend, but he only has 105 yards on the season.
One thing too. Eli Manning >>>>>>>>>>>>> Mark Sanchez. Eli this year is year has been a top QB and Sanchez is middle of the pack. The Giants have the sixth ranked passing offense and the Jets have the 22nd ranked pass offense even after playing the Patriots once. Sanchez played the Pats a month ago and passed for 166 yards which other than the Baltimore game was a season low.
The Jets could easily win this game and the Jets could pass all over the Pats, but the Jets passing offense isn't nearly as good as the Giants even without Hakeem Nick. This year there are few areas on the offense where the Jets beat the Giants even with several key players out for the Giants.