That makes no sense. You don't decide to throw to the RB before the play, you throw to him if he is open.
It is entirely possible to get wide open on a handful of plays and covered on others. Your theory assumes we choose who to throw to and do it whether he is open or not.
After re-watching the game, the only real mistake I noticed that Brady made in terms of who to throw it to was on the INT on the deep ball to Gronk. I have said before that even though it was a major mistake, it was a defensible one in some ways. HOWEVER, on that play Hernandez was *WIDE* open (no Giant within 10-15 yards of him) about 10-15 yards downfield on the right. It would have been an easy 15-20 yard gain had Brady thrown it there. It would have set the Pats up with a first down somewhere in the range of NY's 35-40.
But other than that, I thought he generally threw to the open man.