Its an excellent idea to run the score up to at least 40, then try new offensive and defensive plays and schemes you will use on your next opponent.We never took the Rams seriously, and tried a lot of new plays and personnel right off the bat. That was just a mistake.
Patriots can put the game away by the middle of the 3rd quarter or sooner, if they get a point buffer ,and then play out some new schemes, and personnel, to see where they are at, or if they are productive.
If you score 90pts and they all work, so what.
I think its the advantage of playing a horrible team , like the colts. Personally, if I coached, I might even onside kick with a 40pt lead. It would tell me where my specials teams were and how good is my Red zone defense vs a bad offense.