You have to agree that Peyton has a much tougher task than Brady. He was insane in that game and usually is in the regular season. It is just a matter of time before he gets that post season monkey off his back and wins multiple championships. Sorry, but as much as I love Brady and wouldn't want anyone else, Manning can do things Brady can't...end of story!
The biggest difference between the Pats and the Colts are their priorities in the front office. The Colts have a priority to keep Manning happy and make sure he gets and keeps the weapons he needs on offense. These guys, including the OL, have a chemistry that is off the charts and that has been the prioirty. Keeping this unit together (with very little lost personnel - James) and therefore continue to build on what is great year after year. Manning knows going in to Camp just who and what that offense is and he runs it to damned near perfection!
The Pats on the other hand have made defense their priority and tried to establish more continuity within the defense in keeping these guys together. Of course, that being said, the Pats have a pay structure that is tight and even though they have lost some key players on defense like Law, they have kept their focus mainly on the DL and the LB's. They have have a feel and chemistry and seem to be right up there (barring injury) in defense stats year after year (ala the Colts offense).
Bottom line is Indy, with that awful defense, might be the first team with an offense good enough to finally win the SB and although Manning has incredible weapons at his disposal, he is the main reason that offense is so amazing. He can pass like no QB I have ever seen and his command is unparelled at the QB position!