I still haven't seen one person say why 16 games is perfect, what makes that better than 18? Nothing it's just an arbitrary number we are used to. It might make the chance of injury go up slightly, but if that is what you are worried about go to 12 games.
I watch football, more specifically, I watch the patriots. I really enjoy watching the Patriots play football. I would rather watch them play 18 games that matter than I would watch them play 16 games. I enjoy watching them play in the playoffs because it gives me however many more games to watch them.
I certainly hope that no one gets injured, but that is the risk that they take whenever they go out there to play. It is the same risk that college, high school, and pop warner players take every time they go out to play. That is part of what makes football the game it is. The risk that those players take whenever they put on their helmets.
Now I understand that at some point the game may suffer because there is only so much that these players can take, and there probably is some point at which the quality of the game will diminish. Yet I fail to see how doing away with two meaningless preseason games, and replacing them with two games that count will diminish the quality of the season at all.