Kind of a pity, really. Obviously, as one of our main rivals, any loss for the Colts is a boon for us. But it's always sad when one of the greats doesn't get to play. People always said that the consecutive starts record was the most important one to Manning, so I'm sure this has the potential to be very heartbreaking for him. He'll obviously do everything he can to play, but it sounds like it won't be in his (or the team's) best interest.
It'll be interesting to see how this plays out, and it will probably be a hint as to how Peyton's career will come to a close. More so than any other player and organization relationship, the Colts are Manning's team, often to a fault. The Colts will likely yield to his bidding as long as he pleases. The all-time records likely mean a lot to him, but they may come at the expense of his body and efficiency, as well as the team's winning. How long will Manning play into his declining years, and might it hurt his standing in history? Who knows. Hopefully years from now, he'll retire with his health and dignity instead of forcing himself beyond usefulness in the dogged pursuit of Favre's records.
